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Persistent Babesiosis: from Immune Deficiency to Antimicrobial Resistance – Tufts Medicine’s Edouard Vannier, PharmD, PhD

Date: October 31, 2024
Time: 12:00 pm - 1:00 pm
Location: Hybrid: In-Person and Zoom (Audience limited to Tufts Members and Affiliates; please contact CIMAR@tufts.edu for more details.)
Levy CIMAR Science Lunch | Tufts Lyme Disease Initiative

Please join us for a seminar from Tufts Medicine’s Edouard Vannier, PharmD, PhD, on “Persistent Babesiosis: from Immune Deficiency to Antimicrobial Resistance.” Babesiosis is a sometimes life-threatening infectious disease caused by parasites that invade and destroy red blood cells. Babesiosis has been on the rise in the northeastern United States and often develops following the bite of a deer tick infected with Babesia microti. This talk is jointly sponsored by the Levy CIMAR and the Tufts Lyme Disease Initiative, and will take place on Thursday, October 31, at 12 noon in Behrakis Auditorium and by Zoom (details to come).

Dr. Vannier is an assistant professor at Tufts University’s School of Medicine and a researcher in the Division of Geographic Medicine & Infectious Diseases at Tufts Medical Center. He is also a member of the Tufts Lyme Disease Initiative. Dr. Vannier and his colleagues are doing research on how to prevent babesiosis, supported by the NIH and DoD.

You can learn more about Dr. Vannier’s work on Tufts Medicine’s Babesiosis Research Program website.

Past Events:

This presentation will feature a collaborative One Health effort that began at Tufts University in 2016 in the area of antimicrobial resistance.  Claire Fellman, DVM, and Shira Doron, MD, will discuss research, quality improvement, and inter-hospital efforts to support human and animal health including enhanced infection prevention and control, hospital stewardship initiatives, and student mentorship. Drs. Fellman and Doron will also introduce the mission and efforts of the Tufts University Center for the Integrated Management of Antimicrobial Resistance (CIMAR).

Dr. Shira Doron is an Infectious Disease physician, the Hospital Epidemiologist at Tufts Medical Center, and the Chief Infection Control Officer for Tufts Medicine. She is a Professor of Medicine at Tufts University School of Medicine. Dr. Doron is the immediate past chair of the Infectious Diseases Society of America’s Antimicrobial Stewardship Centers of Excellence subcommittee and a member of the society’s Practice and Quality Committee and highly pathogenic avian influenza task force. She holds a contract with the Massachusetts Department of Public Health, funded by the Centers for Disease Control and Prevention, to support healthcare facilities throughout the region in efforts to improve antimicrobial stewardship and infection prevention.
Dr. Claire Fellman is an Associate Professor of small animal internal medicine and clinical pharmacology at Tufts University. Claire co-chairs the Infection Control and Antimicrobial Stewardship Team at the Foster Hospital for Small Animals and leads research efforts seeking to adapt antimicrobial stewardship strategies used in human hospitals to companion animal veterinary settings. Claire’s clinical interests include infectious and immune-mediated diseases.

Please join us for a Levy CIMAR Seminar from Angelika Gründling, PhD, a Professor of Molecular Microbiology at Imperial College London whose research combines genetic, biochemical, and structural approaches to provide mechanistic insight into cell wall synthesis and nucleotide signaling pathways in Staphylococcus aureus and Listeria monocytogenes. Prof. Gründling will present “From the Staphylococcal Cell Wall to Nucleotide Signalling and Halfway Back” on Thursday, May 30th, at 12 noon in M&V 412 (4th floor, 136 Harrison Ave.) and on Zoom (details to come).

Prof. Gründling is spending a sabbatical year in the Rudner and Bernhardt Labs at Harvard Medical School, where her research goal is to fill gaps in the understanding of how the bacterial membrane is built. Please click the following links to learn more about Prof. Gründling’s work at Imperial College London or about her sabbatical research at Harvard.

Please join us for a seminar from Brown University’s Christina Cuomo, PhD, a Professor of Molecular Microbiology & Immunology who works to identify mechanisms of virulence and drug resistance that can be used to guide and refine treatment decisions. Dr. Cuomo will present on “Genomic Epidemiology and Evolution of Drug Resistance in Candida auris” on Thursday, March 28th, at 12 noon both in person and by Zoom (details to come).

Dr. Cuomo and team utilize genomic approaches to study the evolution of human fungal pathogenic species, taking comparative, population genomic, and microevolutionary approaches to identify genes and variants associated with phenotypes linked to virulence and drug resistance and to characterize how genome structure evolves.

Dr. Cuomo is also the Director of the Fungal Genomics Group and Associate Director in the Genomic Center for Infectious Diseases at the Broad Institute of MIT and Harvard. Dr. Cuomo’s work at the Broad has led to major insights into the unique features of pathogenic species, how genomes evolve, variation with pathogen populations, antifungal drug resistance, and genes involved in host interaction.

You can learn more about her research here and here.

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